Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11793913 | 0.98 | KMT2A (0.71) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL3462941 | 0.90 | EGFR (0.66) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL3462939 | 0.90 | EGFR (0.66) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL10576308 | 0.86 | MAPT (0.86) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL9515073 | 0.85 | LMNA (0.69) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL5218010 | 0.85 | GAA (0.64) | KMT2ALMNAPOLBMEN1ALDH1A1 | |
| Phenacetin SCHEMBL23280 | 0.85 | KMT2A (1.00) | KMT2ALMNACYP1A2POLBMEN1 | |
| Phenacetin SCHEMBL18894356 | 0.85 | KMT2A (1.00) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL9312707 | 0.85 | POLB (1.00) | KMT2ALMNACYP1A2POLBMEN1 | |
| SCHEMBL4104467 | 0.84 | MAPT (0.76) | KMT2ALMNACYP1A2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840610-B2 | Compositions and methods for the degradation of waste polypropylene | NOVOLOOP, INC. (US) | 2023-12-12 | — | — | US | claimed |
| US-20190054067-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | SAINT JOSEPH'S UNIVERSITY | 2019-02-21 | — | — | US | claimed |
| EP-3429563-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | University of the Sciences in Philadelphia (US) | 2019-01-23 | — | — | EP | claimed |
| WO-2017160813-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | UNIVERSITY OF THE SCIENCES (US) | 2017-09-21 | — | — | WO | claimed |
| US-20190054067-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | SAINT JOSEPH'S UNIVERSITY | 2019-02-21 | — | — | US | disclosed |
| EP-3429563-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | University of the Sciences in Philadelphia (US) | 2019-01-23 | — | — | EP | disclosed |
| US-10005739-B2 | Quinazolinone and isoquinolinone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2018-06-26 | — | — | US | disclosed |
| WO-2017160813-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | UNIVERSITY OF THE SCIENCES (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20160272595-A1 | QUINAZOLINONE AND ISOQUINOLINONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-09-22 | — | — | US | disclosed |
| EP-3061749-A1 | QUINAZOLINONE AND ISOQUINOLINONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2016-08-31 | — | — | EP | disclosed |
| CN-102746296-B | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-10-28 | — | — | CN | disclosed |
| CN-102746297-B | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-08-26 | — | — | CN | disclosed |
| US-20090054472-A1 | Pyrazolopyrimidine Derivatives or Pharmaceutically Acceptable Salts Thereof | TEIJIN PHARMA LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| US-7473694-B2 | Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof | TEIJIN PHARMA LIMITED (JP) | 2009-01-06 | — | — | US | disclosed |
| EP-1864986-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-20070173519-A1 | Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof | TEIJIN PHARMA LIMITED | 2007-07-26 | — | — | US | disclosed |
| US-4798905-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | disclosed |
| US-4396621-A | ANALGESICS, ANTIIMFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |
| US-4320138-A | ANTIINFLAMMATORY AGENTS FOR ARTHRITIS, GOUT | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4260779-A | ANALGESICS, ANTIINFLAMMATORY, DIURETICS | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054472-A1 | Pyrazolopyrimidine Derivatives or Pharmaceutically Acceptable Salts Thereof | MAPKAPK2, MAPKAPK5, MAPKAPK3 | KMT2A 979/4885LMNA 4673/4885CYP1A2 3758/4885 |
| US-20160272595-A1 | QUINAZOLINONE AND ISOQUINOLINONE DERIVATIVE | NQO2, SDHA, CYP3A5 | KMT2A 2733/4885LMNA 3526/4885CYP1A2 59/4885 |
| US-20070173519-A1 | Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof | MAPKAPK2, MAPKAPK5, MAPKAPK3 | KMT2A 979/4885LMNA 4673/4885CYP1A2 3758/4885 |
| US-10005739-B2 | Quinazolinone and isoquinolinone derivative | NQO2, SDHA, CYP3A5 | KMT2A 2733/4885LMNA 3526/4885CYP1A2 59/4885 |
| US-20190054067-A1 | COMPOSITIONS AND METHODS FOR TREATING COMPULSIVE-LIKE BEHAVIOR IN A SUBJECT | CHRNA4, CHRNA5, CHRNE | KMT2A 400/4885LMNA 4852/4885CYP1A2 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.