Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891511 | 0.78 | TSHR (0.70) | ABCC1ALDH1A1ATMHPGDTSHR | |
| SCHEMBL7030087 | 0.77 | KDM4E (0.66) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL9267838 | 0.76 | LMNA (0.59) | ABCC1ALDH1A1ATMHPGDTSHR | |
| SCHEMBL30951635 | 0.75 | ESR1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL1913885 | 0.75 | ESR1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL24079457 | 0.75 | ESR1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL4188666 | 0.74 | ACHE (0.54) | ALDH1A1ATMHSD17B10MEN1KMT2A | |
| SCHEMBL3456312 | 0.74 | SLC6A2 (0.70) | ABCC1ATMHPGDTSHRMEN1 | |
| Aspirin SCHEMBL9776218 | 0.74 | KDM4E (0.60) | ABCC1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9001760 | 0.74 | TSHR (0.79) | ABCC1ALDH1A1ATMHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2023930-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. Organon (NL) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008020866-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON | 2008-02-21 | — | — | WO | disclosed |