Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10331768 | 0.86 | ESR1 (0.45) | ESR1ESR2ERN1TRIM24TYR | |
| SCHEMBL15065087 | 0.83 | ERN1 (0.49) | ESR1ESR2ERN1 | |
| SCHEMBL15698095 | 0.81 | ERN1 (0.47) | ERN1CYP1A2LMNAHSD17B10 | |
| SCHEMBL2372753 | 0.78 | ERN1 (0.45) | ESR1ESR2ERN1TRIM24TYR | |
| SCHEMBL23061789 | 0.78 | NSD2 (0.43) | ERN1HSD17B10 | |
| SCHEMBL17654724 | 0.78 | ESR1 (0.49) | ESR1ESR2ERN1TRIM24TYR | |
| SCHEMBL12760794 | 0.78 | TRIM24 (0.60) | ERN1CYP1A2TRIM24TYRTRIM33 | |
| SCHEMBL29956684 | 0.77 | ERN1 (0.44) | ESR1ESR2ERN1CYP1A2TRIM24 | |
| SCHEMBL3067367 | 0.77 | ERN1 (0.44) | ESR1ESR2ERN1CYP1A2TRIM24 | |
| SCHEMBL589343 | 0.76 | ERN1 (0.55) | ERN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470821-B2 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2008-12-30 | — | — | US | claimed |
| EP-1641807-B1 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIV TOULOUSE (FR) | 2008-06-18 | — | — | EP | claimed |
| JP-2007516184-A | — | — | 2007-06-21 | — | — | JP | claimed |
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2007-02-22 | — | — | US | claimed |
| EP-1641807-A2 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2006-04-05 | — | — | EP | claimed |
| WO-2005012313-A2 | ALDOLASE-INHIBITING AROMATIC COMPOUNDS | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2005-02-10 | — | — | WO | claimed |
| EP-2476713-B1 | Resist underlayer film composition and patterning process using the same | SHINETSU CHEMICAL CO (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-9230827-B2 | Method for forming a resist under layer film and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-05 | — | — | US | disclosed |
| US-9230827-B2 | Method for forming a resist under layer film and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-05 | — | — | US | disclosed |
| US-9046764-B2 | Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-06-02 | — | — | US | disclosed |
| US-9046764-B2 | Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-06-02 | — | — | US | disclosed |
| EP-2816409-A1 | Method for forming a resist under layer film and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-20140335692-A1 | METHOD FOR FORMING A RESIST UNDER LAYER FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-13 | — | — | US | disclosed |
| EP-2476713-A1 | Resist underlayer film composition and patterning process using the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-07-18 | — | — | EP | disclosed |
| US-20090137532-A1 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2009-05-28 | — | — | US | disclosed |
| US-7470821-B2 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2008-12-30 | — | — | US | disclosed |
| EP-1641807-B1 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIV TOULOUSE (FR) | 2008-06-18 | — | — | EP | disclosed |
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2007-02-22 | — | — | US | disclosed |
| EP-1641807-A2 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005012313-A2 | ALDOLASE-INHIBITING AROMATIC COMPOUNDS | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | ALDOA, DERA, AKR1B1 | ESR1 2320/4885ESR2 1901/4885ERN1 2031/4885 |
| US-20090137532-A1 | Aldolase-inhibiting aromatic compounds | ALDOA, DERA, AKR1B1 | ESR1 2320/4885ESR2 1901/4885ERN1 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.