Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718098 | 0.81 | CYP19A1 (0.44) | HTTL3MBTL1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL1476827 | 0.80 | CYP19A1 (0.50) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL1898463 | 0.74 | MEN1 (0.46) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL15603984 | 0.69 | ALDH1A1 (0.42) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL15605846 | 0.68 | BRCA1 (0.42) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL1478293 | 0.67 | ALDH1A1 (0.51) | HTTL3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL5605880 | 0.65 | MAPT (0.44) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL29425649 | 0.64 | ALDH1A1 (0.45) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL2339098 | 0.64 | ALDH1A1 (0.45) | TSHRHTTL3MBTL1GLAALDH1A1 | |
| SCHEMBL1812493 | 0.64 | ALDH1A1 (0.57) | TSHRHTTL3MBTL1GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635596-B2 | adding to a lubricating oil a diaminoanhraquinone derivative provided that the compound has at least one substituent selected from among cyano, nitro, hydroxy, hydroxyalkyl, amide, carboxyl, ester and unsaturated alkyl; measuring spectroscopic property of the oil to determine degradation of such compound | ROHM AND HAAS COMPANY (US) | 2009-12-22 | — | — | US | disclosed |
| EP-1672052-B1 | Method for monitoring degradation of lubricating oils | ROHM & HAAS (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1672052-A1 | Method for monitoring degradation of lubricating oils | Rohm and Haas Company (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20060128025-A1 | adding to a lubricating oil a diaminoanhraquinone derivative provided that the compound has at least one substituent selected from among cyano, nitro, hydroxy, hydroxyalkyl, amide, carboxyl, ester and unsaturated alkyl; measuring spectroscopic property of the oil to determine degradation of such compound | ROHM AND HAAS COMPANY | 2006-06-15 | — | — | US | disclosed |