Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | AR | P10275 | 17/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4174955 | 0.87 | AR (0.74) | MAOBAR | |
| SCHEMBL4193059 | 0.87 | AR (0.58) | MAOBAR | |
| SCHEMBL4601213 | 0.86 | AR (0.55) | MAOBAR | |
| SCHEMBL4201266 | 0.85 | AR (0.67) | MAOBAR | |
| SCHEMBL3648539 | 0.82 | MAOB (1.00) | MAOBIMPDH2 | |
| SCHEMBL427002 | 0.81 | MAOB (0.74) | MAOBIMPDH2 | |
| SCHEMBL4196449 | 0.80 | AR (0.59) | AR | |
| SCHEMBL10469104 | 0.80 | MAOB (0.68) | MAOBIMPDH2 | |
| SCHEMBL4206295 | 0.79 | AR (0.67) | AR | |
| SCHEMBL4199094 | 0.79 | AR (0.57) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170886-A1 | ANDROGEN MODULATORS | AR, NR5A1, SHBG | MAOB 1336/4885AR 1/4885IMPDH2 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.