Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.74 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190952 | 0.88 | MAOB (0.62) | MAOBIMPDH2MAOALMNACYP1A2 | |
| SCHEMBL4753464 | 0.88 | MAOB (0.74) | MAOBIMPDH2MAOAALOX5MRGPRX4 | |
| SCHEMBL4435816 | 0.88 | MAOB (0.57) | MAOBMAOACYP1A2CYP2C19NR4A2 | |
| SCHEMBL13735988 | 0.87 | MAOB (0.57) | MAOBIMPDH2MAOAALOX5MRGPRX4 | |
| SCHEMBL4424283 | 0.87 | MAOB (0.56) | MAOBMAOAMRGPRX4NR4A2 | |
| SCHEMBL3648539 | 0.85 | MAOB (1.00) | MAOBIMPDH2MAOAALOX5MRGPRX4 | |
| SCHEMBL18639804 | 0.85 | MAOB (0.55) | MAOBMAOAMRGPRX4TRPV4CYP11B1 | |
| SCHEMBL20465388 | 0.85 | MAOB (0.76) | MAOBMAOATRPV4CYP11B1CYP11B2 | |
| SCHEMBL8135327 | 0.85 | MAOB (0.54) | MAOBIMPDH2MAOACYP11B1CYP11B2 | |
| SCHEMBL188561 | 0.85 | MAOB (0.55) | MAOBMAOACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368114-A1 | INDAZOLES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX INC (US) | 2024-11-07 | — | — | US | disclosed |
| CN-110105346-B | Optionally substituted quinoline compounds | 卫材R&D管理有限公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-3995495-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2022-05-11 | — | — | EP | disclosed |
| EP-3995495-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-20210198220-A1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-07-01 | — | — | US | disclosed |
| US-11001563-B2 | SSAO inhibitor | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-11 | — | — | US | disclosed |
| EP-3133075-B1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-12-30 | — | — | EP | disclosed |
| US-20200115352-A1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. | 2020-04-16 | — | — | US | disclosed |
| EP-3626717-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2020-03-25 | — | — | EP | disclosed |
| US-RE47193-E1 | Selectively substituted quinoline compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| WO-1999043763-A1 | LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1999-09-02 | — | — | WO | disclosed |
| EP-0835254-B1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1999-09-01 | — | — | EP | disclosed |
| EP-0891358-A1 | OXAZOLIDIN-2-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-20 | — | — | EP | disclosed |
| US-5843975-A | Oxazolidinone derivatives, their preparation and therapeutical use | SYNTHELABO (FR) | 1998-12-01 | — | — | US | disclosed |
| EP-0835254-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997013768-A1 | OXAZOLIDIN-2-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-04-17 | — | — | WO | disclosed |
| WO-1996038444-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1996-12-05 | — | — | WO | disclosed |
| US-5312564-A | Halogen-containing, optically active liquid crystal compound and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1994-05-17 | — | — | US | disclosed |
| US-4780242-A | BIPHENYL ESTERS | CHISSO CORPORATION (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0197677-A2 | Halogen-containing, optically active liquid crystal compound and liquid crystal composition containing same | Chisso Corporation (JP) | 1986-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11001563-B2 | SSAO inhibitor | SSB, ASAH2, AOX1 | MAOB 78/4885IMPDH2 551/4885MAOA 74/4885 |
| US-20210198220-A1 | SSAO INHIBITOR | SSB, ASAH2, AOX1 | MAOB 78/4885IMPDH2 551/4885MAOA 74/4885 |
| US-20240368114-A1 | INDAZOLES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CSNK1G3, CSNK1A1, CSNK1D | MAOB 2502/4885IMPDH2 726/4885MAOA 2340/4885 |
| US-20200115352-A1 | SSAO INHIBITOR | SSB, ASAH2, AOX1 | MAOB 78/4885IMPDH2 551/4885MAOA 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.