Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581528 | 0.84 | ACHE (0.47) | ACHEBACE1MEN1MAPTKMT2A | |
| SCHEMBL2484777 | 0.77 | ACHE (0.49) | ACHEMAOA | |
| SCHEMBL4202516 | 0.77 | ACHE (0.45) | ACHEBACE1MAOA | |
| SCHEMBL4197678 | 0.74 | ACHE (0.46) | ACHEBACE1MAOA | |
| SCHEMBL5716849 | 0.73 | ACHE (0.49) | ACHEBACE1 | |
| SCHEMBL3661432 | 0.72 | ACHE (0.49) | ACHECYP1A2MAOA | |
| SCHEMBL5952663 | 0.71 | ACHE (0.46) | ACHE | |
| SCHEMBL29507295 | 0.71 | ACHE (0.53) | ACHEBACE1 | |
| SCHEMBL16489153 | 0.71 | ACHE (0.53) | ACHEBACE1MAOA | |
| SCHEMBL5952853 | 0.70 | ACHE (0.45) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636245-B1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-20060252637-A1 | Bisindenyl zirconium complexes for use in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| EP-1636245-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004106351-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |