SCHEMBL3661432

SCHEMBL3661432

Cc1cc2c(c(Br)c1C)CC(C)C2=O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.49
MAOA P21397 4/20 0.34
CYP1A2 P05177 1/20 0.33
MAOB P27338 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990219 0.84 ACHE (0.53) ACHEMAOAMAOB
SCHEMBL3742970 0.81 ACHE (0.50) ACHEMAOA
SCHEMBL15931777 0.81 ACHE (0.41) ACHE
SCHEMBL15931789 0.81 ACHE (0.41) ACHE
SCHEMBL19313325 0.77 ACHE (0.38) ACHEMAOA
SCHEMBL1454366 0.77 ACHE (0.59) ACHEMAOAMAOB
SCHEMBL17135796 0.76 ACHE (0.49) ACHEMAOAMAOB
SCHEMBL17147586 0.76 ACHE (0.49) ACHEMAOAMAOB
SCHEMBL3688423 0.76 ACHE (0.41) ACHE
SCHEMBL3685904 0.76 ACHE (0.41) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569532-B2 Catalysts BOREALIS TECHNOLOGY OY (FI) 2013-10-29 US disclosed
US-8569532-B2 Catalysts BOREALIS TECHNOLOGY OY (FI) 2013-10-29 US disclosed
US-8569532-B2 Catalysts BOREALIS TECHNOLOGY OY (FI) 2013-10-29 US disclosed
US-20120252993-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2012-10-04 US disclosed
US-20120252993-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2012-10-04 US disclosed
US-20120252993-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2012-10-04 US disclosed
US-20100305286-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2010-12-02 US disclosed
US-20100305286-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2010-12-02 US disclosed
US-20100305286-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2010-12-02 US disclosed
EP-2215129-A2 CATALYSTS Borealis Technology OY (FI) 2010-08-11 EP disclosed
WO-2009027075-A2 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2009-03-05 WO disclosed
WO-2009027075-A2 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2009-03-05 WO disclosed
EP-1636245-B1 BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2009-02-25 EP disclosed
US-20060252637-A1 Bisindenyl zirconium complexes for use in the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2006-11-09 US disclosed
EP-1636245-A1 BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS Basell Polyolefine GmbH (DE) 2006-03-22 EP disclosed
WO-2004106351-A1 BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252993-A1 CATALYSTS CYP4F11, COXFA4, CYP2F1 ACHE 1896/4885MAOA 187/4885CYP1A2 52/4885
US-20100305286-A1 CATALYSTS H1-2, CCNL2, H1-3 ACHE 3963/4885MAOA 4132/4885CYP1A2 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.