2-Pyrrolidone

2-Pyrrolidone

SCHEMBL4193115

C=CC(=O)O.O=C1CCCN1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.62
CRBN Q96SW2 3/20 0.54
FKBP5 Q13451 1/20 0.54
LMNA P02545 1/20 0.42
KDM4E B2RXH2 3/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.39
ITGB3 P05106 1/20 0.33
ITGB1 P05556 1/20 0.33
ITGAV P06756 1/20 0.33
ITGA4 P13612 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL11253981 1.00 OR51E2 (0.62) OR51E2CRBNFKBP5LMNAKDM4E
2-Pyrrolidone SCHEMBL10583107 0.94 OR51E2 (0.56) OR51E2CRBNFKBP5LMNAKDM4E
Caprolactam SCHEMBL2325626 0.92 CRBN (0.61) OR51E2CRBNFKBP5LMNAKDM4E
2-Pyrrolidone SCHEMBL2489556 0.86 OR51E2 (0.60) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27650892 0.86 OR51E2 (0.60) OR51E2CRBNFKBP5LMNAKDM4E
2-Pyrrolidone SCHEMBL10798548 0.85 OR51E2 (0.46) OR51E2CRBNFKBP5LMNAKDM4E
Fumaric Acid SCHEMBL9716897 0.85 OR51E2 (0.65) OR51E2CRBNFKBP5LMNAKDM4E
Fumaric Acid SCHEMBL9716900 0.85 OR51E2 (0.65) OR51E2CRBNFKBP5LMNAKDM4E
Maleic Acid SCHEMBL1737647 0.85 OR51E2 (0.65) OR51E2CRBNFKBP5LMNAKDM4E
2-Pyrrolidone SCHEMBL27486853 0.85 OR51E2 (0.54) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118308029-A Chemical mechanical polishing solution 齐芯微(绍兴)电子材料科技有限公司 2024-07-09 CN claimed
CN-114349922-B Flexible dual-cured resin composition and preparation method of molded body thereof 浙江华峰新材料有限公司 2024-01-23 CN claimed
CN-113121747-B Photosensitive resin and preparation method and application thereof 浙江华峰新材料有限公司 2022-08-02 CN claimed
CN-114349922-A Flexible dual-curing resin composition and preparation method of forming body thereof 浙江华峰新材料有限公司 2022-04-15 CN claimed
CN-113121747-A Photosensitive resin and preparation method and application thereof 浙江华峰新材料有限公司 2021-07-16 CN claimed
CN-109266261-A A kind of student's environmentally protective glue and preparation method thereof 喻泰阁 2019-01-25 CN claimed
CN-104797661-A Multifunctional coating structure and method for forming the same SAMSUNG ELECTRONICS CO LTD 2015-07-22 CN claimed
US-20080274296-A1 ENERGY-CURABLE COATING/ADHESIVE COMPOSITIONS CONTAINING CHLORINATED POLYOLEFINS SCOTT LEVI F 2008-11-06 US claimed
US-20040228998-A1 Curable film preform compositions PERMATEX, INC. 2004-11-18 US claimed
WO-2004098472-A1 TRANSDERMAL DELIVERY SYSTEMS AND METHODS WATSON PHARMACEUTICALS, INC. (US) 2004-11-18 WO claimed
US-20040202704-A1 Transdermal delivery systems and methods WATSON PHARMACEUTICALS, INC. 2004-10-14 US claimed
EP-0557087-B1 Aqueous aerosol hair-spray compositions with a relatively low content of volatile organic compounds REVLON CONSUMER PROD CORP (US) 1995-12-06 EP claimed
CN-114349922-B Flexible dual-cured resin composition and preparation method of molded body thereof 浙江华峰新材料有限公司 2024-01-23 CN disclosed
CN-117244117-A Medical catheter surface coating processing method and coating composition 安徽翰兴医疗科技有限公司 2023-12-19 CN disclosed
US-20230047848-A1 ADDITION CURABLE SILICONE ADHESIVE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-02-16 US disclosed
EP-4073193-A1 ADDITION CURABLE SILICONE ADHESIVE COMPOSITIONS Momentive Performance Materials Inc. (US) 2022-10-19 EP disclosed
US-20040202704-A1 Transdermal delivery systems and methods WATSON PHARMACEUTICALS, INC. 2004-10-14 US disclosed
CN-1385921-A Projel composition, its dehydration method, secondary cell and double electric layer capacitor NISSHIN SPINNING (JP) 2002-12-18 CN disclosed
WO-1997030092-A2 HYDROGELS INNOVATIVE TECHNOLOGIES LIMITED (GB) 1997-08-21 WO disclosed
EP-0332336-A2 Antimicrobial composition KURITA WATER INDUSTRIES LTD. (JP) 1989-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040202704-A1 Transdermal delivery systems and methods LPXN, GNRHR, TECR OR51E2 2095/4885CRBN 4394/4885FKBP5 483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.