⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924271 | 0.82 | HSD17B3 (0.38) | — | |
| SCHEMBL8470589 | 0.82 | HSD17B3 (0.38) | — | |
| SCHEMBL5489008 | 0.77 | TYR (0.41) | — | |
| SCHEMBL22458615 | 0.76 | GABRA1 (0.38) | — | |
| SCHEMBL21705667 | 0.76 | HSD17B3 (0.40) | — | |
| SCHEMBL7177601 | 0.76 | TYR (0.43) | — | |
| SCHEMBL29923984 | 0.76 | HCAR2 (0.37) | — | |
| SCHEMBL11274887 | 0.74 | AKR1B1 (0.42) | — | |
| SCHEMBL18867816 | 0.73 | KDM4E (0.48) | — | |
| SCHEMBL29557236 | 0.73 | HTR2C (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032628-A2 | POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES | Sabic Innovative Plastics IP B.V. (NL) | 2009-03-11 | — | — | EP | claimed |
| WO-2007106296-A2 | POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2007-09-20 | — | — | WO | claimed |
| US-20200216467-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-07-09 | — | — | US | disclosed |
| US-9956222-B2 | Quinazoline derivative as tyrosine-kinase inhibitor, preparation method therefor and application thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2018-05-01 | — | — | US | disclosed |
| US-20170136023-A1 | QUINAZOLINE DERIVATIVE AS TYROSINE-KINASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2017-05-18 | — | — | US | disclosed |
| US-9586939-B2 | Quinazoline derivative as tyrosine-kinase inhibitor, preparation method therefor and application thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2017-03-07 | — | — | US | disclosed |
| EP-1761382-A1 | MULTILAYER COMPOSITES WITH SPECIAL VISUAL EFFECTS | GENERAL ELECTRIC COMPANY (US) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006007419-A1 | MULTILAYER COMPOSITES WITH SPECIAL VISUAL EFFECTS | GENERAL ELECTRIC COMPANY (US) | 2006-01-19 | — | — | WO | disclosed |
| EP-0583484-B1 | STYRENIC RESIN COMPOSITION | IDEMITSU KOSAN CO (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5391611-A | High strength, impact strength,heat resistance, fireproof | IDEMITSU KOSAN CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0583484-A1 | STYRENIC RESIN COMPOSITION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-4373065-A | Optically isotropic devices | XEROX CORPORATION (US) | 1983-02-08 | — | — | US | disclosed |