SCHEMBL5489008

SCHEMBL5489008

CCCCCc1cc2ccc1o2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.41
ALOX15 P16050 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
TLR8 Q9NR97 1/20 0.39
LIPG Q9Y5X9 1/20 0.38
KCNH2 Q12809 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
ERAP1 Q9NZ08 1/20 0.36
CTRC Q99895 1/20 0.36
HCAR2 Q8TDS4 2/20 0.36
SRC P12931 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7177601 0.98 TYR (0.43) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL8470589 0.86 HSD17B3 (0.38) MEN1KMT2ACYP3A4ALOX5MAPT
SCHEMBL9581030 0.75 ALOX5 (0.46) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL25415956 0.74 ALOX5 (0.40) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL878089 0.72 ALOX5 (0.43) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL25417724 0.72 ALOX5 (0.43) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL18889039 0.69 ALOX5 (0.50) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL28737834 0.68 HCAR2 (0.40) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL8792802 0.68 LIPG (0.42) TYRALOX15MEN1KMT2ACYP3A4
SCHEMBL7606700 0.67 CTRC (0.40) TYRALOX15MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007045944-A METHOD FOR PRODUCING POLY(2-ARYL-1,4-PHENYLENE ETHER) SHOWA DENKO KK 2007-02-22 JP disclosed