Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920031 | 0.92 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2GAATDP1MAPT | |
| SCHEMBL2930475 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2GAATDP1MAPT | |
| SCHEMBL2932348 | 0.83 | HTT (0.46) | ALDH1A1SMN1; SMN2MAPTPOLBKMT2A | |
| SCHEMBL8919153 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAATDP1MAPT | |
| SCHEMBL2929120 | 0.82 | HTT (0.36) | ALDH1A1SMN1; SMN2POLBCNR1CNR2 | |
| SCHEMBL8920042 | 0.81 | POLB (0.45) | ALDH1A1SMN1; SMN2GAAMAPTPOLB | |
| SCHEMBL2925238 | 0.80 | CNR1 (0.35) | ALDH1A1SMN1; SMN2CNR1CNR2KMT2A | |
| SCHEMBL13356459 | 0.77 | CNR1 (0.34) | ALDH1A1SMN1; SMN2POLBCNR1CNR2 | |
| SCHEMBL9089099 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2GAATDP1MAPT | |
| SCHEMBL8920797 | 0.76 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MAPTPOLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098257-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE CATIONIC DIAMINO-N,N-DIHYDROPYRAZOLONE DERIVATIVE | L'OREAL (FR) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009098257-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE CATIONIC DIAMINO-N,N-DIHYDROPYRAZOLONE DERIVATIVE | L'OREAL (FR) | 2009-08-13 | — | — | WO | disclosed |