Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585962 | 0.83 | CCR6 (0.60) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL7752775 | 0.83 | CCR6 (0.52) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL10557920 | 0.83 | ALDH1A1 (0.47) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL6827731 | 0.82 | ALDH1A1 (0.53) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL1897393 | 0.81 | CCR6 (0.51) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL7356270 | 0.80 | CCR6 (0.43) | CCR6PAX8ALDH1A1LTA4H | |
| SCHEMBL16586897 | 0.79 | CCR6 (0.63) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL10556507 | 0.79 | ALDH1A1 (0.50) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL17747886 | 0.78 | CCR6 (0.48) | CCR6PAX8ALDH1A1TDP1MAPK1 | |
| SCHEMBL9110508 | 0.78 | CCR6 (0.61) | CCR6PAX8ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009014730-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |