Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 4/20 | 0.38 |
| ▸ | MC3R | P41968 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11428997 | 0.84 | CCR6 (0.42) | CCR6PAX8MC5RMC3RMC4R | |
| SCHEMBL4194136 | 0.80 | CCR6 (0.51) | CCR6PAX8ALDH1A1LTA4H | |
| Sulfuric Acid SCHEMBL8810381 | 0.80 | CCR6 (0.41) | CCR6PAX8ALDH1A1 | |
| Phosphoric Acid SCHEMBL8810333 | 0.80 | CCR6 (0.41) | CCR6PAX8ALDH1A1 | |
| SCHEMBL7514942 | 0.80 | LTA4H (0.42) | CCR6PAX8ALDH1A1LTA4H | |
| SCHEMBL11414742 | 0.80 | CCR6 (0.39) | CCR6PAX8ALDH1A1LTA4H | |
| SCHEMBL17377997 | 0.79 | CCR6 (0.61) | CCR6PAX8MC5RMC3RALDH1A1 | |
| SCHEMBL1299849 | 0.79 | CCR6 (0.57) | CCR6PAX8ITGB3ITGA2B | |
| SCHEMBL9020013 | 0.79 | CCR6 (0.45) | CCR6PAX8ITGB3ITGA2BALDH1A1 | |
| SCHEMBL5033581 | 0.76 | HTT (0.52) | CCR6PAX8KDM4AKDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013817-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |