Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189798 | 0.81 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL4195718 | 0.80 | — | — | |
| SCHEMBL4196172 | 0.77 | DHFR (0.34) | CYP1A2 | |
| SCHEMBL4201277 | 0.76 | CCR9 (0.36) | CYP1A2 | |
| SCHEMBL4194379 | 0.76 | CDK4 (0.36) | CYP1A2 | |
| SCHEMBL6806254 | 0.75 | CDK4 (0.46) | CYP1A2 | |
| SCHEMBL4194383 | 0.74 | CTSS (0.35) | — | |
| SCHEMBL4195717 | 0.73 | BACE1 (0.30) | — | |
| SCHEMBL4186998 | 0.73 | CDK4 (0.43) | — | |
| SCHEMBL4200625 | 0.71 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029145-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | Novartis Ag (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007140222-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2007-12-06 | — | — | WO | disclosed |