SCHEMBL4194448

SCHEMBL4194448

O=C(Oc1ccc(O)cc1)C(Cc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.59
ESR2 Q92731 4/20 0.59
CHRM1 P11229 1/20 0.49
EPHX1 P07099 1/20 0.49
LMNA P02545 3/20 0.45
PTGS2 P35354 2/20 0.45
CYP1A2 P05177 1/20 0.45
PTGS1 P23219 1/20 0.45
SLC6A2 P23975 1/20 0.45
CYP2C19 P33261 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
KLK1 P06870 1/20 0.42
MIF P14174 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11403491 0.87 EPHX1 (0.59) ESR1ESR2CHRM1EPHX1CYP1A2
SCHEMBL10426648 0.85 LMNA (0.46) ESR1ESR2LMNAPTGS2CYP1A2
SCHEMBL5156210 0.80 ESR1 (0.61) ESR1ESR2CHRM1EPHX1LMNA
SCHEMBL27757470 0.80 ESR1 (0.61) ESR1ESR2CHRM1EPHX1LMNA
SCHEMBL8670930 0.80 TSHR (0.49) LMNAPTGS2CYP1A2PTGS1SLC6A2
SCHEMBL14021656 0.80 ESR1 (0.72) ESR1ESR2LMNAPTGS2CYP1A2
SCHEMBL21579844 0.80 LMNA (0.50) ESR1ESR2EPHX1LMNAHSD17B10
SCHEMBL10599433 0.78 DRD3 (0.46) ESR1ESR2LMNAPTGS2CYP1A2
SCHEMBL14941251 0.78 ESR1 (0.49) ESR1ESR2CHRM1LMNACYP1A2
SCHEMBL27667714 0.78 ESR1 (0.83) ESR1ESR2CHRM1EPHX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7164759-A None JP disclosed
JP-5162459-A None JP disclosed
US-11865853-B2 Thermosensitive recording medium and exterior member SONY CORPORATION (JP) 2024-01-09 US disclosed
US-20230311554-A1 Thermosensitive Recording Material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-10-05 US disclosed
EP-4205990-A1 THERMOSENSITIVE RECORDING MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2023-07-05 EP disclosed
CN-113260516-B Thermosensitive recording medium 株式会社理光 2023-05-02 CN disclosed
US-11571921-B2 Thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2023-02-07 US disclosed
CN-113260516-A Thermosensitive recording medium 株式会社理光 2021-08-13 CN disclosed
US-20210178796-A1 THERMOSENSITIVE RECORDING MEDIUM AND EXTERIOR MEMBER SONY CORPORATION (JP) 2021-06-17 US disclosed
EP-3670205-B1 THERMOSENSITIVE RECORDING MEDIUM RICOH CO LTD (JP) 2021-02-17 EP disclosed
EP-2724334-A1 THERMOSENSITIVE RECORDING LABEL Ricoh Company, Ltd. (JP) 2014-04-30 EP disclosed
US-8702896-B2 Heat-sensitive adhesive material, adhered article, process and apparatus for thermally activating the heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2014-04-22 US disclosed
WO-2013069581-A1 THERMOSENSITIVE RECORDING LABEL RICOH COMPANY, LTD. (JP) 2013-05-16 WO disclosed
US-20090050268-A1 Heat-sensitive adhesive material, adhered article, process and apparatus for thermally activating the heat-sensitive adhesive material MORITA MITSUNOBU 2009-02-26 US disclosed
JP-H07164759-A THERMAL RECORDING MATERIAL NIPPON KAYAKU CO LTD 1995-06-27 JP disclosed
EP-0468459-B1 Heat-sensitive recording material KANZAKI PAPER MFG CO LTD (JP) 1994-02-16 EP disclosed
JP-H05162459-A RECORDING MATERIAL NIPPON KAYAKU CO LTD 1993-06-29 JP disclosed
US-5206210-A Alpha naphthoic acid, storage stability KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-04-27 US disclosed
EP-0468459-A1 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-01-29 EP disclosed
US-4912079-A Thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1990-03-27 US disclosed