Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197351 | 0.90 | HSD17B10 (0.50) | TSHRELANECYP2C19CYP1A2HSD17B10 | |
| SCHEMBL16080197 | 0.83 | LMNA (0.54) | TSHRLMNASLC6A2SLC6A3MIF | |
| SCHEMBL8268036 | 0.83 | LMNA (0.54) | TSHRLMNASLC6A2SLC6A3MIF | |
| SCHEMBL28320251 | 0.82 | FPR2 (0.54) | TSHRELANECYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL11432413 | 0.80 | NPC1 (0.47) | TSHRELANELMNACYP2C19SLC6A2 | |
| SCHEMBL4194448 | 0.80 | ESR1 (0.59) | LMNACYP2C19CYP1A2PTGS1SLC6A2 | |
| SCHEMBL265176 | 0.78 | ALDH1A1 (0.58) | TSHRCYP2C19SLC6A2SLC6A3HSD17B10 | |
| SCHEMBL97654 | 0.78 | ELANE (0.46) | TSHRELANELMNACYP2C19CYP1A2 | |
| SCHEMBL12764099 | 0.78 | ALDH1A1 (0.58) | TSHRCYP2C19SLC6A2SLC6A3HSD17B10 | |
| SCHEMBL10359066 | 0.78 | ELANE (0.46) | TSHRELANELMNACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837452-A | HEATING CELLS IN SOLUTION CONTAINING NONIONIC SURFACTANT DETERGENT AND CHELATE COMPOUND | GEN-PROBE INCORPORATED (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1994028420-A1 | METHOD OF DETECTION OF BACTERIA | RHONE POULENC DIAGNOSTICS LTD (GB) | 1994-12-08 | — | — | WO | disclosed |