SCHEMBL4194791

SCHEMBL4194791

c1ccc(N(CCN(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.52
MTNR1A P48039 3/20 0.50
MTNR1B P49286 3/20 0.50
KDM4E B2RXH2 2/20 0.42
SIGMAR1 Q99720 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425499 0.97 KCNH2 (0.50) KCNH2MTNR1AMTNR1BKDM4ESIGMAR1
SCHEMBL28613602 0.89 KCNH2 (0.45) KCNH2MTNR1AMTNR1BKDM4ESIGMAR1
SCHEMBL4970515 0.88 KCNH2 (0.50) KCNH2MTNR1AMTNR1BSIGMAR1
SCHEMBL138431 0.88 KCNH2 (0.50) KCNH2MTNR1AMTNR1BKDM4ESIGMAR1
SCHEMBL10707846 0.87 MTNR1A (0.47) KCNH2MTNR1AMTNR1BKDM4ESIGMAR1
SCHEMBL6441273 0.85 KCNH2 (0.47) KCNH2MTNR1AMTNR1BKDM4ESIGMAR1
SCHEMBL10830280 0.85 KCNH2 (0.48) KCNH2MTNR1AMTNR1BSIGMAR1
SCHEMBL4194250 0.85 KCNH2 (0.48) KCNH2MTNR1AMTNR1BSIGMAR1
SCHEMBL18979892 0.84 CYP3A4 (0.62) KCNH2MTNR1AMTNR1BKDM4EL3MBTL1
SCHEMBL158097 0.83 MTNR1A (0.48) KCNH2MTNR1AMTNR1BKDM4ESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119608075-A Industrial trimethylolpropane continuous production method and system thereof 天津海成能源工程技术有限公司 2025-03-14 CN claimed
CN-118388402-A Continuous preparation method of 3-cyano-4-trifluoromethyl pyridine 山东京博生物科技有限公司 2024-07-26 CN claimed
EP-0099924-B1 IMMUNOLOGIC ASSAY FOR DETERMINING PRESENCE OF A PHOSPHOLIPID IN BIOLOGICAL FLUID HANA BIOLOGICS, INC. (US) 1986-05-07 EP claimed
US-4481373-A CATALYTIC OXIDATION OF OLEFINS IN PRESENCE OF TERTIARY AMINE OF AMIDE TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1984-11-06 US claimed
WO-2026104818-A1 COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2026-05-21 WO disclosed
CN-119608075-A Industrial trimethylolpropane continuous production method and system thereof 天津海成能源工程技术有限公司 2025-03-14 CN disclosed
CN-118388402-A Continuous preparation method of 3-cyano-4-trifluoromethyl pyridine 山东京博生物科技有限公司 2024-07-26 CN disclosed
US-20240228682-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2024-07-11 US disclosed
EP-4337703-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W. R. Grace & Co.-Conn (US) 2024-03-20 EP disclosed
WO-2023166948-A1 (METH)ACRYLATE-TERMINATED POLYPHENYLENE ETHER OLIGOMER, AND RESIN COMPOSITION, VARNISH, PREPREG, AND CURED PRODUCT CONTAINING SAME 本州化学工業株式会社 2023-09-07 WO disclosed
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst MITSUI CHEMICALS, INC. (JP) 2023-07-04 US disclosed
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst MITSUI CHEMICALS, INC. (JP) 2023-07-04 US disclosed
EP-0086281-B1 PREPARATION OF CARBAMATES USING A PALLADIUM-CONTAINING CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-05-15 EP disclosed
US-4503140-A Radiation-sensitive compositions of polymers containing a π-metal carbonyl complex of conjugated polyolefin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-05 US disclosed
US-4481373-A CATALYTIC OXIDATION OF OLEFINS IN PRESENCE OF TERTIARY AMINE OF AMIDE TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1984-11-06 US disclosed
US-4474978-A Preparation of carbamates SHELL OIL COMPANY (US) 1984-10-02 US disclosed
EP-0095269-A2 Radiation-sensitive compositions of polymers containing a pi-metal carbonyl complex of conjugated polyolefin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-11-30 EP disclosed
EP-0068866-A1 Method of manufacturing acetone or methyl ethyl ketone TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1983-01-05 EP disclosed
US-4095022-A PHOSPHORUS COMPOUNDS, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1978-06-13 US disclosed
US-4026935-A FROM N-(HYDROXYALKYL)-MORPHOLINE COMPOUND, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst OXER1, COG6, CBR1 KCNH2 2468/4885MTNR1A 1946/4885MTNR1B 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.