SCHEMBL4195079

SCHEMBL4195079

COC(=O)[C@@H](N)CSCC(N)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.47
ARG2 P78540 1/20 0.47
NOS2 P35228 3/20 0.46
NOS1 P29475 2/20 0.46
NOS3 P29474 1/20 0.46
KIF11 P52732 5/20 0.42
SLC1A1 P43005 2/20 0.40
SLC7A5 Q01650 1/20 0.39
GFPT1 Q06210 1/20 0.39
BHMT Q93088 1/20 0.38
BHMT2 Q9H2M3 1/20 0.38
PTGS1 P23219 1/20 0.37
SLC7A11 Q9UPY5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160075 0.88 KIF11 (0.42) ARG1ARG2NOS2NOS1NOS3
SCHEMBL12438522 0.88 KIF11 (0.42) ARG1ARG2NOS2NOS1NOS3
SCHEMBL1815745 0.88 KIF11 (0.42) ARG1ARG2NOS2NOS1NOS3
SCHEMBL1815741 0.88 KIF11 (0.42) ARG1ARG2NOS2NOS1NOS3
SCHEMBL12438514 0.88 KIF11 (0.42) ARG1ARG2NOS2NOS1NOS3
SCHEMBL12438513 0.88 KIF11 (0.42) ARG1ARG2NOS2NOS1NOS3
Cystine SCHEMBL25390642 0.86 KIF11 (0.41) ARG1ARG2NOS2NOS1NOS3
Hydrochloric Acid SCHEMBL22290069 0.86 KIF11 (0.41) ARG1ARG2NOS2NOS1NOS3
Hydrochloric Acid SCHEMBL21611699 0.86 KIF11 (0.41) ARG1ARG2NOS2NOS1NOS3
Hydrochloric Acid SCHEMBL21611698 0.86 KIF11 (0.41) ARG1ARG2NOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531803-B Cyclic galanin analogs and uses thereof 兰硫代佩普有限公司 2021-11-12 CN claimed
CN-106170492-B Cyclic Apelin analogs 兰硫代佩普有限公司 2020-08-21 CN claimed
CN-106188253-B Antibacterial peptide Lexapeptide and preparation method and application thereof 上海交通大学 2020-08-18 CN claimed
EP-3268383-A1 CYCLIC GALANIN-ANALOGS AND USES THEREOF LanthioPep B.V. (NL) 2018-01-17 EP claimed
CN-107531803-A Cyclic galanin analogs and uses thereof 兰硫代佩普有限公司 2018-01-02 CN claimed
US-20170107257-A1 CYCLIC APELIN ANALOGS LANTHIOPEP B.V. (NL) 2017-04-20 US claimed
EP-3122764-A1 CYCLIC APELIN ANALOGS LanthioPep B.V. (NL) 2017-02-01 EP claimed
CN-106170492-A Cyclic Apelin analogs 兰硫代佩普有限公司 2016-11-30 CN claimed
WO-2016146513-A1 CYCLIC GALANIN-ANALOGS AND USES THEREOF LANTHIOPEP B.V. (NL) 2016-09-22 WO claimed
WO-2015147641-A1 CYCLIC APELIN ANALOGS LANTHIOPEP B.V. (NL) 2015-10-01 WO claimed
WO-2025032101-A1 NEW COMPOSITION FOR ANTI-AGE TREATMENT OF SKIN L'ORÉAL (FR) 2025-02-13 WO disclosed
CN-118561963-A Nicotine acetylcholine receptor peptide antagonist conotoxin compositions and related methods 格罗制药公司 2024-08-30 CN disclosed
CN-118420728-A Lanothalapeptide and preparation method and application thereof 河北省科学院生物研究所 2024-08-02 CN disclosed
EP-4392048-A1 PROBIOTIC BACTERIA COMPOSITION FOR INHIBITING FUNGAL PROLIFERATION Lactobio A/S (DK) 2024-07-03 EP disclosed
CN-118139633-A Probiotic composition for inhibiting fungal proliferation 莱托生物股份有限公司 2024-06-04 CN disclosed
EP-0342658-B1 Biosynthetic process for the preparation of chemical compounds THOMAE GMBH DR K (DE) 1994-05-11 EP disclosed
EP-0543195-A2 Biosynthetic process for the preparation of proteins Dr. Karl Thomae GmbH (DE) 1993-05-26 EP disclosed
EP-0342658-A1 Biosynthetic process for the preparation of chemical compounds Dr. Karl Thomae GmbH (DE) 1989-11-23 EP disclosed
EP-0083612-A1 NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS FLORK, Michel (FR) 1983-07-20 EP disclosed
WO-1983000146-A1 NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS FLORK, MICHEL 1983-01-20 WO disclosed