Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438513 | 1.00 | KIF11 (0.42) | KIF11NOS2NOS1NOS3SLC1A1 | |
| SCHEMBL1815741 | 1.00 | KIF11 (0.42) | KIF11NOS2NOS1NOS3SLC1A1 | |
| SCHEMBL1815745 | 1.00 | KIF11 (0.42) | KIF11NOS2NOS1NOS3SLC1A1 | |
| SCHEMBL160075 | 1.00 | KIF11 (0.42) | KIF11NOS2NOS1NOS3SLC1A1 | |
| SCHEMBL12438514 | 1.00 | KIF11 (0.42) | KIF11NOS2NOS1NOS3SLC1A1 | |
| Cystine SCHEMBL25390642 | 0.98 | KIF11 (0.41) | KIF11NOS2NOS1NOS3SLC1A1 | |
| Hydrochloric Acid SCHEMBL22290069 | 0.98 | KIF11 (0.41) | KIF11NOS2NOS1NOS3SLC1A1 | |
| Hydrochloric Acid SCHEMBL3315835 | 0.98 | KIF11 (0.41) | KIF11NOS2NOS1NOS3SLC1A1 | |
| Hydrochloric Acid SCHEMBL21611699 | 0.98 | KIF11 (0.41) | KIF11NOS2NOS1NOS3SLC1A1 | |
| Hydrochloric Acid SCHEMBL21611698 | 0.98 | KIF11 (0.41) | KIF11NOS2NOS1NOS3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040261-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2015-05-26 | — | — | US | disclosed |
| US-9040261-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2015-05-26 | — | — | US | disclosed |
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110177173-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-21 | — | — | US | disclosed |
| WO-2011062640-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177173-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | GLS, PKD1, CLIC1 | KIF11 4118/4885NOS2 1392/4885NOS1 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.