SCHEMBL4196300

SCHEMBL4196300

CO[SiH](CCC(C)c1ccccc1)OC

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.48
TAAR1 Q96RJ0 3/20 0.45
TRPA1 O75762 4/20 0.42
AOC3 Q16853 2/20 0.41
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18662221 0.84 HRH1 (0.45) TAAR1ALDH1A1HPGD
SCHEMBL6280516 0.81 RIPK1 (0.67) RIPK1TAAR1TRPA1AOC3
SCHEMBL9230452 0.80 TAAR1 (0.48) RIPK1TAAR1TRPA1AOC3ALDH1A1
SCHEMBL28205540 0.79 SCN4A (0.43)
Lithium SCHEMBL30777534 0.79 RIPK1 (0.64) RIPK1TAAR1TRPA1AOC3
SCHEMBL5213988 0.79 RIPK1 (0.64) RIPK1TAAR1TRPA1AOC3
SCHEMBL3157412 0.76 RIPK1 (0.52) RIPK1TAAR1TRPA1AOC3
SCHEMBL1599408 0.76 RIPK1 (0.52) RIPK1TAAR1TRPA1AOC3
SCHEMBL7084838 0.75 HTR2A (0.31)
SCHEMBL6681320 0.74 RIPK1 (0.59) RIPK1TAAR1TRPA1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0974596-B1 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING (US) 2003-03-05 EP claimed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP claimed
EP-2032588-B1 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT DOW CORNING (US) 2012-08-08 EP disclosed
WO-2012091154-A1 METHOD OF PRODUCING A HYDROLYZABLE SILICON-CONTAINING COMPOUND WASEDA UNIVERSITY (JP) 2012-07-05 WO disclosed
US-20090270646-A1 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE DOW CORNING CORPORATION 2009-10-29 US disclosed
EP-2032588-A2 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT Dow Corning Corporation (US) 2009-03-11 EP disclosed
WO-2007149201-A2 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT DOW CORNING CORPORATION (US) 2007-12-27 WO disclosed
EP-0974596-B1 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING (US) 2003-03-05 EP disclosed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP disclosed
EP-0679654-B1 Process for preparation of organooxysilanes DOW CORNING (US) 1999-07-07 EP disclosed
US-5914421-A Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 1999-06-22 US disclosed
EP-0679654-A1 Process for preparation of organooxysilanes DOW CORNING CORPORATION (US) 1995-11-02 EP disclosed
US-5374761-A Process for preparation of organooxysilanes CORNING CORPORATION (US) 1994-12-20 US disclosed