SCHEMBL7084838

SCHEMBL7084838

CO[SiH](CCC(SSSSC(CC[SiH](OC)OC)c1ccccc1)c1ccccc1)OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.31
HRH1 P35367 2/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18662221 0.78 HRH1 (0.45) HTR2AHRH1KMT2A
SCHEMBL4196300 0.75 RIPK1 (0.48)
SCHEMBL28205540 0.74 SCN4A (0.43)
SCHEMBL5163795 0.73 MEN1 (0.32) HTR2AHRH1KMT2A
SCHEMBL6551627 0.67 KMT2A (0.30) KMT2A
SCHEMBL28716147 0.66 HTR2A (0.41) HTR2AHRH1KMT2A
SCHEMBL775358 0.66 AOC3 (0.44) HTR2AHRH1
SCHEMBL5832167 0.66 SIGMAR1 (0.42) HTR2AHRH1
SCHEMBL9230452 0.63 TAAR1 (0.48) HTR2AHRH1
SCHEMBL6904970 0.63 HTR2A (0.31) HTR2AHRH1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941872-B1 Rubber composition reinforced with silica and tire with tread thereof GOODYEAR TIRE & RUBBER (US) 2003-08-06 EP disclosed