⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280653 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL5842344 | 0.97 | — | — | |
| SCHEMBL9309574 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL4201088 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL29170713 | 0.78 | — | — | |
| SCHEMBL250773 | 0.78 | — | — | |
| SCHEMBL4199296 | 0.74 | — | — | |
| SCHEMBL22485676 | 0.73 | — | — | |
| SCHEMBL7517212 | 0.73 | — | — | |
| SCHEMBL106292 | 0.72 | NFKB1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223875-A1 | SIRNA OF ANGIOPOIETIN-LIKE 3 (ANGPTL3) AND USE THEREOF | Nanopeptide (Qingdao) Biotechnology Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| US-20220151731-A1 | LASER APPARATUS AND METHOD OF USE FOR DENTAL SURGERY | MILLENNIUM HEALTHCARE TECH INC (US) | 2022-05-19 | — | — | US | disclosed |
| WO-2014110705-A9 | HETEROCYCLE-SUBSTITUTED TETRACYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2015-03-05 | — | — | WO | disclosed |
| WO-2014110705-A1 | HETEROCYCLE-SUBSTITUED TETRACYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2014-07-24 | — | — | WO | disclosed |
| CN-102448920-A | Antiviral compounds and uses thereof | ABBOTT LAB | 2012-05-09 | — | — | CN | disclosed |
| US-20090012054-A1 | Cephem Compounds and Use as Antimicrobial Agents | ASTELLAS PHARMA INC. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1994035-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007119511-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | ASTELLAS PHARMA INC. (JP) | 2007-10-25 | — | — | WO | disclosed |