Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | SDHB | P21912 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 2/20 | 0.31 |
| ▸ | STAT1 | P42224 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191507 | 0.83 | NPC1 (0.33) | SMN1; SMN2LMNATP53GLP1RNPSR1 | |
| SCHEMBL4195166 | 0.78 | GLP1R (0.31) | GLP1R | |
| SCHEMBL4199144 | 0.74 | CYP1A2 (0.34) | LMNA | |
| SCHEMBL15985987 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1LMNATP53GLP1R | |
| SCHEMBL4192247 | 0.68 | TRPV1 (0.34) | SMN1; SMN2L3MBTL1LMNAMEN1POLB | |
| SCHEMBL4194121 | 0.64 | — | — | |
| SCHEMBL4205153 | 0.64 | — | — | |
| SCHEMBL12496395 | 0.63 | HRH4 (0.37) | SMN1; SMN2HPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL15747526 | 0.63 | LMNA (0.36) | SMN1; SMN2LMNATP53GLP1RNPSR1 | |
| SCHEMBL6259470 | 0.63 | GLP1R (0.32) | SMN1; SMN2L3MBTL1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2006288-A1 | AMINOPYRIDINE DERIVATIVE AND PLANT DISEASE CONTROL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | DPYD, PM20D2, PDCD11 | SMN1; SMN2 3171/4885L3MBTL1 417/4885LMNA 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.