Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943563 | 0.88 | POLB (0.36) | TRPV1CASP7BRCA1TSHRPOLB | |
| SCHEMBL4205235 | 0.78 | SMN1; SMN2 (0.37) | TSHRPOLBSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL4191507 | 0.73 | NPC1 (0.33) | SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL4201476 | 0.73 | ADORA2A (0.40) | TRPV1TSHRPOLBALDH1A1MEN1 | |
| SCHEMBL5525205 | 0.71 | NPSR1 (0.44) | CASP7BRCA1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL5474300 | 0.71 | TSHR (0.41) | CASP7BRCA1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL4197196 | 0.69 | ADORA2A (0.36) | TRPV1CASP7BRCA1TSHRPOLB | |
| SCHEMBL4197121 | 0.68 | SMN1; SMN2 (0.40) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3944735 | 0.64 | HTR2A (0.39) | TSHRPOLBSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL4195166 | 0.63 | GLP1R (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2006288-A1 | AMINOPYRIDINE DERIVATIVE AND PLANT DISEASE CONTROL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | DPYD, PM20D2, PDCD11 | TRPV1 4718/4885CASP7 1329/4885BRCA1 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.