Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927763 | 0.78 | OR51E2 (0.42) | OR51E2HTT | |
| SCHEMBL9752586 | 0.76 | OR51E2 (0.40) | OR51E2 | |
| SCHEMBL2169407 | 0.74 | CXCR2 (0.35) | — | |
| SCHEMBL3441578 | 0.74 | OR51E2 (0.39) | OR51E2 | |
| SCHEMBL11559471 | 0.72 | OR51E2 (0.37) | OR51E2 | |
| SCHEMBL27719997 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL28646053 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL8864068 | 0.69 | ALDH1A1 (0.38) | — | |
| Sulfuric Acid SCHEMBL276967 | 0.69 | OR51E2 (0.42) | OR51E2 | |
| SCHEMBL28351233 | 0.68 | SLC7A5 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574216-B1 | Inhibitors of phosphatidyl Myo-Inositol Cycle | UNIV GEORGETOWN (US) | 2009-03-11 | — | — | EP | disclosed |
| US-20070213398-A1 | INHIBITORS OF PHOSPHATIDYL MYO-INOSITOL CYCLE | KOZIKOWSKI ALAN P | 2007-09-13 | — | — | US | disclosed |
| US-7153843-B2 | Inhibitors of phosphatidyl myo-inositol cycle | GEORGETOWN UNIVERSITY (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1574216-A1 | Inhibitors of phosphatidyl Myo-Inositol Cycle | GEORGETOWN UNIVERSITY (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20040192770-A1 | Inhibitors of phosphatidyl myo-inositol cycle | NIH - DEITR | 2004-09-30 | — | — | US | disclosed |
| US-6667340-B1 | 3-deoxy-D-myo-inositol analogs; inhibiting cell proliferation and/or differentiation; promotion of cell apoptosis | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2003-12-23 | — | — | US | disclosed |
| EP-1119364-A4 | INHIBITORS OF PHOSPHATIDYL MYO-INOSITOL CYCLE | UNIV GEORGETOWN (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1119364-A1 | INHIBITORS OF PHOSPHATIDYL MYO-INOSITOL CYCLE | GEORGETOWN UNIVERSITY (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6245754-B1 | 3-DEOXY-D-MYO-INOSITOL ANALOGS; PHOSPHATIDYL INOSITOL 3-KINASE INHIBITORS; ANTICARCINOGENIC AND ANTITUMOR AGENTS | NIH - DEITR | 2001-06-12 | — | — | US | disclosed |
| WO-2000000206-A1 | INHIBITORS OF PHOSPHATIDYL MYO-INOSITOL CYCLE | GEORGETOWN UNIVERSITY (US) | 2000-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192770-A1 | Inhibitors of phosphatidyl myo-inositol cycle | PIP5K1B, PPIP5K2, PIP5K1A | OR51E2 4786/4885HTT 4875/4885 |
| US-20070213398-A1 | INHIBITORS OF PHOSPHATIDYL MYO-INOSITOL CYCLE | PIP5K1B, PPIP5K2, PIP5K1A | OR51E2 4786/4885HTT 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.