SCHEMBL4197813

SCHEMBL4197813

CC(=COc1ccccc1-c1ccccc1)C(=O)OCCCOc1cccc(OCCCOC(=O)C(C)=COc2ccccc2-c2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 2/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
FFAR4 Q5NUL3 2/20 0.42
KDM4E B2RXH2 11/20 0.42
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197864 0.92 FFAR4 (0.47) L3MBTL1HTTTDP1FFAR4KDM4E
SCHEMBL4197503 0.90 FFAR4 (0.48) HTTTDP1FFAR4KDM4EALDH1A1
SCHEMBL4202057 0.90 KDM4E (0.49) L3MBTL1HTTKDM4EALDH1A1KMT2A
SCHEMBL4186160 0.89 FFAR4 (0.47) L3MBTL1HTTFFAR4KDM4EALDH1A1
SCHEMBL4193711 0.89 KDM4E (0.51) L3MBTL1HTTKDM4EALDH1A1KMT2A
SCHEMBL4198447 0.88 PPARG (0.40) L3MBTL1FFAR4KDM4EALDH1A1KMT2A
SCHEMBL4202648 0.86 FFAR4 (0.45) L3MBTL1LMNAMAPK1HTTTDP1
SCHEMBL4184758 0.85 HDAC1 (0.46) FFAR4KDM4EPPARGPPARDPPARA
SCHEMBL4184738 0.85 PPARD (0.46) L3MBTL1LMNAMAPK1FFAR4KDM4E
SCHEMBL4190846 0.85 KDM4E (0.40) L3MBTL1LMNAMAPK1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 L3MBTL1 2124/4885LMNA 4549/4885MAPK1 1412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.