Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568915 | 0.86 | MCHR1 (0.47) | MCHR1RIPK1 | |
| SCHEMBL2206901 | 0.82 | MCHR1 (0.49) | MCHR1KDM4E | |
| SCHEMBL29818908 | 0.82 | MCHR1 (0.49) | MCHR1KDM4E | |
| SCHEMBL26508753 | 0.81 | MCHR1 (0.48) | MCHR1RIPK1 | |
| SCHEMBL2207261 | 0.81 | NFKB1 (0.49) | MCHR1RIPK1 | |
| SCHEMBL14858080 | 0.81 | MCHR1 (0.48) | MCHR1RIPK1 | |
| SCHEMBL25819244 | 0.80 | HTR1B (0.57) | MCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL1500529 | 0.79 | SLC6A4 (0.43) | MCHR1ALDH1A1MAPTLMNA | |
| SCHEMBL19291756 | 0.79 | MCHR1 (0.46) | MCHR1RIPK1 | |
| SCHEMBL25822155 | 0.79 | MCHR1 (0.46) | MCHR1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |