Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25819244 | 0.88 | HTR1B (0.57) | MCHR1HTR1BALDH1A1KDM4EPDE4A | |
| SCHEMBL2206901 | 0.85 | MCHR1 (0.49) | MCHR1HTR1BKDM4E | |
| SCHEMBL29818908 | 0.85 | MCHR1 (0.49) | MCHR1HTR1BKDM4E | |
| SCHEMBL4568915 | 0.83 | MCHR1 (0.47) | MCHR1HTR1B | |
| Ammonia Solution, Strong SCHEMBL4198347 | 0.79 | MCHR1 (0.48) | MCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL25822152 | 0.78 | PARP10 (0.49) | BRD4 | |
| SCHEMBL2209601 | 0.78 | KMT2A (0.45) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL19291756 | 0.76 | MCHR1 (0.46) | MCHR1 | |
| SCHEMBL14858080 | 0.76 | MCHR1 (0.48) | MCHR1BRD4 | |
| SCHEMBL2207261 | 0.76 | NFKB1 (0.49) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | MCHR1 666/4885HTR1B 960/4885ALDH1A1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.