Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424388 | 0.89 | BRD4 (0.39) | ACHEBRD4CREBBPNPC1RAB9A | |
| SCHEMBL5952410 | 0.87 | ACHE (0.57) | ACHEMAPTMAOAMAOBMEN1 | |
| SCHEMBL4201024 | 0.83 | METAP1 (0.35) | ACHEBRD4CREBBPMAPTTSHR | |
| SCHEMBL4194430 | 0.83 | ACHE (0.51) | ACHEBRD4TSHRMAOAMAOB | |
| SCHEMBL5689519 | 0.81 | ACHE (0.49) | ACHEBRD4CREBBPMAOAMAOB | |
| SCHEMBL4191823 | 0.74 | ACHE (0.59) | ACHEBRD4 | |
| SCHEMBL1021838 | 0.74 | ACHE (0.44) | ACHEBRD4CREBBPMAOAMAOB | |
| SCHEMBL2423464 | 0.71 | ACHE (0.41) | ACHEBRD4CREBBPMAOAMAOB | |
| SCHEMBL5951241 | 0.71 | ACHE (0.47) | ACHEBRD4CREBBPMAOAMAOB | |
| SCHEMBL5716849 | 0.71 | ACHE (0.49) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636245-B1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-20060252637-A1 | Bisindenyl zirconium complexes for use in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| EP-1636245-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004106351-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |