Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.59 |
| ▸ | METAP1 | P53582 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953177 | 0.85 | ACHE (0.56) | ACHEMETAP1 | |
| SCHEMBL5952410 | 0.83 | ACHE (0.57) | ACHEMETAP1 | |
| SCHEMBL4194430 | 0.79 | ACHE (0.51) | ACHEBRD4 | |
| SCHEMBL5716849 | 0.79 | ACHE (0.49) | ACHE | |
| SCHEMBL2481939 | 0.75 | ACHE (1.00) | ACHEMETAP1PARP10 | |
| SCHEMBL29893908 | 0.75 | ACHE (1.00) | ACHEMETAP1PARP10 | |
| SCHEMBL2484416 | 0.75 | ACHE (0.73) | ACHEMETAP1PARP10PARP11 | |
| SCHEMBL4198355 | 0.74 | ACHE (0.47) | ACHEBRD4 | |
| SCHEMBL5951259 | 0.74 | ACHE (0.47) | ACHE | |
| SCHEMBL5951788 | 0.74 | ACHE (0.53) | ACHEMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636245-B1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-20060252637-A1 | Bisindenyl zirconium complexes for use in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| EP-1636245-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004106351-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |