⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247691 | 0.77 | GRM5 (0.36) | — | |
| SCHEMBL5378152 | 0.74 | KDM4E (0.38) | — | |
| Hydrochloric Acid SCHEMBL5573936 | 0.73 | KDM4E (0.37) | — | |
| SCHEMBL6466370 | 0.71 | MAPT (0.34) | — | |
| SCHEMBL3816886 | 0.69 | CCR1 (0.38) | — | |
| SCHEMBL6272101 | 0.67 | CYP3A4 (0.48) | — | |
| SCHEMBL4182663 | 0.67 | MAPT (0.46) | — | |
| SCHEMBL2970013 | 0.66 | TSHR (0.38) | — | |
| SCHEMBL24998828 | 0.66 | GABRA5 (0.48) | — | |
| SCHEMBL14480149 | 0.66 | GPR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642899-B1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2012-08-15 | — | — | EP | claimed |
| US-7223764-B2 | 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2007-05-29 | — | — | US | claimed |
| EP-1642899-A1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2006-04-05 | — | — | EP | claimed |
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2005-01-27 | — | — | US | claimed |
| EP-1642899-B1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-1642899-B1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| CN-101328152-B | Piperazidine compound and pyridine compound | KOWA CO | 2011-06-08 | — | — | CN | disclosed |
| EP-1642899-A4 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2009-02-25 | — | — | EP | disclosed |
| CN-101328152-A | Piperazidine compound and pyridine compound | KOWA CO (JP) | 2008-12-24 | — | — | CN | disclosed |
| CN-100404529-C | 2, 4-bis (trifluoroethoxy) pyridine compound and medicine containing the same | KOWA CO (JP) | 2008-07-23 | — | — | CN | disclosed |
| US-7223764-B2 | 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-7223764-B2 | 2,4-bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| CN-1816542-A | 2, 4-bis (trifluoroethoxy) pyridine compound and medicine containing the same | KOWA CO (JP) | 2006-08-09 | — | — | CN | disclosed |
| EP-1642899-A1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2006-04-05 | — | — | EP | disclosed |
| EP-1642899-A1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| US-20050020606-A1 | 2,4-Bis (trifluoroethoxy)pyridine compound and drug containing the compound | KOWA CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| WO-2005003119-A1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO., LTD. (JP) | 2005-01-13 | — | — | WO | disclosed |