SCHEMBL4198741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13779687	0.85	AR (0.59)	ARKDM4EALDH1A1L3MBTL1SLC22A12
	SCHEMBL4197135	0.79	AR (0.48)	ARKDM4EALDH1A1L3MBTL1LMNA
	SCHEMBL4206255	0.78	AR (0.57)	ARKDM4EALDH1A1L3MBTL1LMNA
	SCHEMBL177449	0.77	AR (0.53)	ARKDM4EALDH1A1L3MBTL1NR3C1
	SCHEMBL4192800	0.75	AR (0.52)	ARKDM4EALDH1A1L3MBTL1NR3C1
	SCHEMBL4163780	0.75	AR (0.72)	ARHTR2ASLC6A4KCNH2SLC22A12
	SCHEMBL4168834	0.75	AR (0.72)	ARHTR2ASLC6A4KCNH2SLC22A12
	SCHEMBL4171318	0.74	AR (0.58)	ARHTR2ASLC6A4KCNH2SLC22A12
	SCHEMBL27376804	0.73	AR (0.52)	ARKDM4EALDH1A1L3MBTL1NR3C1
	SCHEMBL410587	0.73	TRPV4 (0.57)	ARKDM4EALDH1A1SLC22A12TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.