Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 14/20 | 0.54 |
| ▸ | CES1 | P23141 | 13/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954899 | 0.83 | CES2 (0.62) | CES2CES1PTPN1GSK3BEGFR | |
| SCHEMBL9682043 | 0.83 | CES2 (0.62) | CES2CES1PTPN1GSK3BEGFR | |
| SCHEMBL17732045 | 0.81 | CES2 (0.52) | CES2CES1PTPN1GSK3BMTNR1A | |
| SCHEMBL6064977 | 0.78 | GPR52 (0.51) | CES2CES1RAB9A | |
| Biphenyl SCHEMBL27937078 | 0.78 | CES2 (0.56) | CES2CES1PTPN1GSK3BRAB9A | |
| SCHEMBL11878948 | 0.77 | CES2 (0.60) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL11878944 | 0.77 | CES2 (0.60) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL3839743 | 0.77 | PTPN1 (0.41) | CES2CES1PTPN1GSK3BMTNR1A | |
| SCHEMBL3839739 | 0.77 | PTPN1 (0.41) | CES2CES1PTPN1GSK3BMTNR1A | |
| SCHEMBL16226903 | 0.75 | CES2 (0.58) | CES2CES1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636245-B1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-20060252637-A1 | Bisindenyl zirconium complexes for use in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| EP-1636245-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004106351-A1 | BISINDENYL ZIRCONIUM COMPLEXES FOR USE IN THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |