Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229272 | 0.85 | PDE4B (0.48) | — | |
| SCHEMBL4218352 | 0.85 | PDE4B (0.48) | — | |
| SCHEMBL4193344 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4ELMNATDP1CCR5 | |
| SCHEMBL4225725 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4ELMNATDP1CCR5 | |
| SCHEMBL4855227 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4ELMNATDP1CCR5 | |
| SCHEMBL14862196 | 0.77 | PDE4B (0.47) | ALDH1A1KDM4ELMNATDP1MEN1 | |
| SCHEMBL2146128 | 0.73 | GRIN1 (0.41) | ALDH1A1LMNATDP1MEN1KMT2A | |
| SCHEMBL4193528 | 0.72 | SLC6A4 (0.44) | — | |
| SCHEMBL4211817 | 0.72 | SLC6A4 (0.44) | — | |
| SCHEMBL26907360 | 0.71 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029609-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | Eli Lilly & Company (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007146758-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |