Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 3/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195359 | 0.69 | ADORA2A (0.40) | ADORA2AADORA3ADORA2BADORA1KDM4E | |
| SCHEMBL4199176 | 0.68 | ADORA2A (0.38) | ADORA2AADORA3ADORA2BADORA1NLRP3 | |
| SCHEMBL10677397 | 0.66 | ADORA2A (0.40) | ADORA2AADORA3ADORA2BADORA1NLRP3 | |
| SCHEMBL4199174 | 0.66 | ADORA2A (0.38) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL26578140 | 0.64 | HSP90AA1 (0.36) | KDM4E | |
| SCHEMBL18218832 | 0.63 | ALDH1A1 (0.44) | ADORA2AADORA3ADORA2BADORA1KDM4E | |
| SCHEMBL27992031 | 0.63 | ADORA2A (0.61) | ADORA2AADORA3ADORA2BADORA1KDM4E | |
| SCHEMBL10162549 | 0.62 | ADORA2A (0.40) | ADORA2AADORA3ADORA2BADORA1KDM4E | |
| SCHEMBL10130932 | 0.62 | ADORA2A (0.38) | ADORA2AADORA3ADORA2BADORA1KDM4E | |
| SCHEMBL12640004 | 0.62 | PCSK9 (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2006288-A1 | AMINOPYRIDINE DERIVATIVE AND PLANT DISEASE CONTROL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | DPYD, PM20D2, PDCD11 | ADORA2A 608/4885ADORA3 765/4885ADORA2B 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.