Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553093 | 0.74 | ADORA2A (0.70) | ADORA2AHTTADORA3ADORA2BADORA1 | |
| SCHEMBL12286453 | 0.72 | ADORA2A (0.43) | ADORA2AKDM4EALDH1A1ADORA3ADORA2B | |
| SCHEMBL31452734 | 0.72 | ADORA2A (0.44) | ADORA2AKDM4EALDH1A1HTTADORA3 | |
| SCHEMBL24920767 | 0.72 | ADORA2A (0.41) | ADORA2AKDM4EALDH1A1HTTADORA3 | |
| SCHEMBL12294434 | 0.72 | NPC1 (0.43) | KDM4EALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL9520962 | 0.71 | SMN1; SMN2 (0.42) | ADORA2AKDM4EHTTADORA3ADORA2B | |
| SCHEMBL2567010 | 0.70 | ALOX15 (0.44) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL12287316 | 0.70 | TBXAS1 (0.38) | ADORA2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18218832 | 0.70 | ALDH1A1 (0.44) | ADORA2AKDM4EALDH1A1HTTADORA3 | |
| SCHEMBL22573751 | 0.70 | RAB9A (0.53) | ADORA2AKDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |