Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hippuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hippuric Acid SCHEMBL27593894 | 1.00 | MME (0.43) | MMEOPRM1OPRD1OPRK1LTA4H | |
| Hippuric Acid SCHEMBL1838491 | 0.94 | OPRD1 (0.49) | OPRM1OPRD1OPRK1 | |
| SCHEMBL4671172 | 0.93 | OPRD1 (0.42) | OPRM1OPRD1OPRK1 | |
| Hippuric Acid SCHEMBL27636786 | 0.88 | GPR139 (0.37) | — | |
| Hippuric Acid SCHEMBL1120609 | 0.88 | GPR139 (0.37) | — | |
| SCHEMBL1666827 | 0.86 | MME (0.44) | MMELTA4H | |
| SCHEMBL29531330 | 0.86 | MME (0.44) | MMELTA4H | |
| SCHEMBL1666829 | 0.86 | MME (0.44) | MMELTA4H | |
| SCHEMBL4671197 | 0.86 | PTPN1 (0.39) | — | |
| Water SCHEMBL29559377 | 0.85 | MME (0.44) | MMELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127841-A1 | Peptide Pet Food Material Having Anti-Stress Action and Palatability-Increasing Effect | SCHOOL JURIDICAL PERSON KITASATO INSTITUTE (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20090028997-A1 | Peptide pet food material having anti-stress action and palatability-increasing effect | SCHOOL JURIDICAL PERSON KITASATO INSTITUTE (JP) | 2009-01-29 | — | — | US | disclosed |