Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15492370 | 0.83 | SMN1; SMN2 (0.39) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL15490024 | 0.80 | TDP1 (0.36) | RAB9ANPC1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL25225679 | 0.79 | HCAR3 (0.33) | — | |
| SCHEMBL2633420 | 0.77 | — | — | |
| Oxalic Acid SCHEMBL27850504 | 0.76 | HCAR2 (0.35) | CA12CA9KMT2AALDH1A1KDM4E | |
| SCHEMBL10933178 | 0.72 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL348086 | 0.72 | MAPT (0.31) | SMN1; SMN2MAPT | |
| SCHEMBL25025280 | 0.71 | HSD17B10 (0.41) | RAB9ANPC1KMT2AALDH1A1KDM4E | |
| SCHEMBL17209686 | 0.71 | KDM4E (0.50) | RAB9ANPC1SMN1; SMN2CA12CA9 | |
| SCHEMBL1321921 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |