Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL4199385 | 0.89 | CCR1 (0.54) | CCR1ABCB11PPARDBRD4 | |
| SCHEMBL4199387 | 0.84 | CCR1 (0.45) | CCR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7263208 | 0.80 | ABCB11 (0.58) | CCR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5583485 | 0.80 | ABCB11 (0.58) | CCR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2061814 | 0.79 | CCR1 (0.74) | CCR1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL5583417 | 0.73 | ABCB11 (0.48) | CCR1KMT2AABCB11LMNASMN1; SMN2 | |
| SCHEMBL5583430 | 0.73 | ABCB11 (0.48) | CCR1ABCB11LMNABRD4 | |
| SCHEMBL5583514 | 0.72 | ABCB11 (0.48) | CCR1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL5583496 | 0.71 | ABCB11 (0.46) | CCR1KMT2APOLBL3MBTL1ABCB11 | |
| SCHEMBL4666533 | 0.70 | ABCB11 (0.61) | CCR1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027105-A2 | NOVEL PROCESS FOR PREPARING INTERMEDIATES OF CCR ANTAGONISTS | AstraZeneca AB (SE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007129960-A2 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF CCR ANTAGONISTS | ASTRAZENECA AB (SE) | 2007-11-15 | — | — | WO | disclosed |