SCHEMBL4199474

SCHEMBL4199474

CO[Si](NC1CCCCC1C)(OC)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.32
TAS1R3 Q7RTX0 4/20 0.31
TAS1R1 Q7RTX1 4/20 0.31
TAS1R2 Q8TE23 3/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4209707 0.98 EPHX1 (0.33) EPHX1ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL4201520 0.81 ALDH1A1 (0.33) EPHX1ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL4205264 0.81 EPHX1 (0.33) EPHX1ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL4361773 0.79 TAS1R3 (0.33) EPHX1ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL4215428 0.78 EPHX1 (0.32) EPHX1POLB
SCHEMBL4202092 0.76 NPSR1 (0.37) ALDH1A1POLB
SCHEMBL4210491 0.76 TAS1R3 (0.36) EPHX1ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL4206954 0.76 NPSR1 (0.37) ALDH1A1POLB
SCHEMBL888443 0.76 NPSR1 (0.37) ALDH1A1POLB
SCHEMBL4202508 0.76 POLB (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed