Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479991 | 0.96 | CCR2 (0.49) | KMT2AMEN1CCR2PKMSCD | |
| SCHEMBL7146589 | 0.93 | KMT2A (0.50) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL3479897 | 0.93 | KMT2A (0.53) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL3480133 | 0.90 | CCR2 (0.51) | KMT2AMEN1CCR2PKMSCD | |
| SCHEMBL7147077 | 0.89 | KMT2A (0.49) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL3480402 | 0.87 | KMT2A (0.51) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL3479998 | 0.86 | KMT2A (0.50) | KMT2AMEN1CCR2PKMSCD | |
| SCHEMBL3479972 | 0.86 | KMT2A (0.52) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL4193054 | 0.86 | CCR2 (0.48) | KMT2AMEN1CCR2PKMSCD | |
| SCHEMBL3480254 | 0.86 | KMT2A (0.55) | KMT2AMEN1PKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |