Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TGM6 | O95932 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147077 | 0.96 | KMT2A (0.49) | KMT2AMEN1PKMTGM2ALDH1A1 | |
| SCHEMBL3479991 | 0.94 | CCR2 (0.49) | KMT2AMEN1PKMALDH1A1CCR2 | |
| SCHEMBL3479972 | 0.94 | KMT2A (0.52) | KMT2AMEN1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL4199519 | 0.93 | KMT2A (0.46) | KMT2AMEN1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL3480402 | 0.91 | KMT2A (0.51) | KMT2AMEN1PKMTGM2ALDH1A1 | |
| SCHEMBL3479897 | 0.91 | KMT2A (0.53) | KMT2AMEN1PKMTGM2ALDH1A1 | |
| SCHEMBL3479854 | 0.90 | KMT2A (0.53) | KMT2AMEN1PKMTGM2ALDH1A1 | |
| SCHEMBL3479998 | 0.89 | KMT2A (0.50) | KMT2AMEN1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL3480133 | 0.88 | CCR2 (0.51) | KMT2AMEN1PKMALDH1A1CCR2 | |
| SCHEMBL3479904 | 0.88 | KMT2A (0.53) | KMT2AMEN1PKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322642-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-07-02 | — | — | EP | claimed |
| WO-2002026733-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |