SCHEMBL4199536

SCHEMBL4199536

COC(=O)C[C@H](NCCC[Si](OC)(OC)OC)C(=O)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020702 1.00 CA12 (0.31) CA12CA1CA2CA9TSHR
SCHEMBL4447143 0.87 TSHR (0.31) TSHR
SCHEMBL4447146 0.87 TSHR (0.31) TSHR
SCHEMBL31042769 0.86 CA12 (0.30) CA12CA1CA2CA9
SCHEMBL31042778 0.86 TSHR (0.33) CA12CA1CA2CA9TSHR
SCHEMBL13040564 0.86 CA12 (0.32) CA12CA1CA2CA9TSHR
SCHEMBL56140 0.84 KMT2A (0.38) TSHR
SCHEMBL196288 0.84 KMT2A (0.38) TSHR
SCHEMBL11905537 0.82
SCHEMBL11905320 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US claimed
EP-2970716-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING Covestro LLC (US) 2016-01-20 EP claimed
US-20150291846-A1 Fast Cure Aspartate Polysiloxane Hybrid Coating COVESTRO LLC 2015-10-15 US claimed
US-9085712-B2 Fast cure aspartate polysiloxane hybrid coating BAYER MATERIALSCIENCE LLC (US) 2015-07-21 US claimed
WO-2014159307-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING BAYER MATERIALSCIENCE LLC (US) 2014-10-02 WO claimed
US-20140272424-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING COVESTRO LLC 2014-09-18 US claimed
EP-3585845-B1 SILOXANE-BASED COATINGS CONTAINING POLYMERS WITH UREA LINKAGES AND TERMINAL ALKOXYSILANES US GOV SEC NAVY (US) 2024-11-20 EP disclosed
US-11499001-B2 Single-component polysiloxane non-skid / non-slip coatings THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-11-15 US disclosed
EP-3983495-A1 SINGLE-COMPONENT POLYSILOXANE NON-SKID / NON-SLIP COATINGS The Government of the United States of America, as represented by the Secretary of the Navy (US) 2022-04-20 EP disclosed
WO-2020129955-A1 MOISTURE-CURABLE HOT-MELT ADHESIVE セメダイン株式会社 2020-06-25 WO disclosed
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US disclosed
EP-2970716-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING Covestro LLC (US) 2016-01-20 EP disclosed
US-20150291846-A1 Fast Cure Aspartate Polysiloxane Hybrid Coating COVESTRO LLC 2015-10-15 US disclosed
US-7635743-B2 alkoxysilane-terminated polyesterurethane copolymer was obtained in presence of bis-(N, N'-dimethylaminoethyl) ether polymerization catalyst; blocked isocyanates; stable storage at a high temperature and cures very rapidly under the atmosphere; for gluing the most diverse substrates BAYER MATERIALSCIENCE AG (DE) 2009-12-22 US disclosed
US-7557173-B2 Prepolymers containing silyl groups, the production thereof and the use of the same in polyurethane foams HENKEL AG & CO. KGAA (DE) 2009-07-07 US disclosed
US-20060142532-A1 Moisture-curing composition and hot-melt adhesive BAYER MATERIALSCIENCE AG 2006-06-29 US disclosed
US-20050234144-A1 Prepolymers containing silyl groups, the production thereof and the use of the same in polyurethane foams HENKEL AG & CO. KGAA (DE) 2005-10-20 US disclosed
US-6545087-B1 Very high molecular weight polyetherurethane propolymers endcapped by reaction with a dialkyl ester of N-(3-alkoxysilylpropyl)aspartic acid BAYER AKTIENGESELLSCHAFT (DE) 2003-04-08 US disclosed
US-5998504-A PROTECTIVE POLYURETHANE COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-07 US disclosed
US-5364955-A Compounds containing alkoxysilane and amino groups BAYER AKTIENGESELLSCHAFT (DE) 1994-11-15 US disclosed