SCHEMBL2020702

SCHEMBL2020702

COC(=O)CC(NCCC[Si](OC)(OC)OC)C(=O)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199536 1.00 CA12 (0.31) CA12CA1CA2CA9TSHR
SCHEMBL4447143 0.87 TSHR (0.31) TSHR
SCHEMBL4447146 0.87 TSHR (0.31) TSHR
SCHEMBL31042769 0.86 CA12 (0.30) CA12CA1CA2CA9
SCHEMBL31042778 0.86 TSHR (0.33) CA12CA1CA2CA9TSHR
SCHEMBL13040564 0.86 CA12 (0.32) CA12CA1CA2CA9TSHR
SCHEMBL56140 0.84 KMT2A (0.38) TSHR
SCHEMBL196288 0.84 KMT2A (0.38) TSHR
SCHEMBL11905537 0.82
SCHEMBL11905320 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US claimed
EP-2970716-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING Covestro LLC (US) 2016-01-20 EP claimed
US-20150291846-A1 Fast Cure Aspartate Polysiloxane Hybrid Coating COVESTRO LLC 2015-10-15 US claimed
US-9085712-B2 Fast cure aspartate polysiloxane hybrid coating BAYER MATERIALSCIENCE LLC (US) 2015-07-21 US claimed
WO-2014159307-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING BAYER MATERIALSCIENCE LLC (US) 2014-10-02 WO claimed
US-20140272424-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING COVESTRO LLC 2014-09-18 US claimed
EP-4660271-A1 COMPOSITION CONTAINING LINEAR AMINOSILANE COMPOUND HAVING CARBOXYLIC ESTER GROUP AND CYCLIC SILAZANE COMPOUND HAVING CARBOXYLIC ESTER GROUP, AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-10 EP disclosed
US-12448552-B2 Adhesive bond between a thermoplastic material and an elastomer composition SIKA TECHNOLOGY AG (CH) 2025-10-21 US disclosed
WO-2025109943-A1 SOLID WATER-SOLUBLE POLYSILOXANE COMPOUND HAVING AMINO ACID-CONTAINING GROUP, AND METHOD FOR PRODUCING SAME 信越化学工業株式会社 2025-05-30 WO disclosed
WO-2025109942-A1 MOLDED PRODUCT CONTAINING INORGANIC PARTICLES AND WATER SOLUBLE POLYSILOXANE COMPOUND HAVING AMINO GROUP, METHOD FOR PRODUCING SAME, AND INORGANIC PARTICLE DISPERSION LIQUID 信越化学工業株式会社 2025-05-30 WO disclosed
US-12240960-B2 Thixotropic agent for curable compositions SIKA TECHNOLOGY AG (CH) 2025-03-04 US disclosed
US-12157707-B2 Curable composition for alkaline substrates SIKA TECHNOLOGY AG (CH) 2024-12-03 US disclosed
EP-3880728-B1 ADHESIVE BOND BETWEEN THERMOPLASTIC AND ELASTOMER COMPOSITION SIKA TECH AG (CH) 2024-10-30 EP disclosed
CN-101525484-A Composition with characteristic of strengthening binding property of poros substrates SIKA TECHNOLOGY AG 2009-09-09 CN disclosed
US-7557173-B2 Prepolymers containing silyl groups, the production thereof and the use of the same in polyurethane foams HENKEL AG & CO. KGAA (DE) 2009-07-07 US disclosed
US-20060142532-A1 Moisture-curing composition and hot-melt adhesive BAYER MATERIALSCIENCE AG 2006-06-29 US disclosed
US-20050234144-A1 Prepolymers containing silyl groups, the production thereof and the use of the same in polyurethane foams HENKEL AG & CO. KGAA (DE) 2005-10-20 US disclosed
US-6545087-B1 Very high molecular weight polyetherurethane propolymers endcapped by reaction with a dialkyl ester of N-(3-alkoxysilylpropyl)aspartic acid BAYER AKTIENGESELLSCHAFT (DE) 2003-04-08 US disclosed
US-5998504-A PROTECTIVE POLYURETHANE COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-07 US disclosed
US-5364955-A Compounds containing alkoxysilane and amino groups BAYER AKTIENGESELLSCHAFT (DE) 1994-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240960-B2 Thixotropic agent for curable compositions INCENP, GJA1, RCC1 CA12 1673/4885CA1 677/4885CA2 1081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.