Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198540 | 0.90 | RAB9A (0.57) | RAB9ANPC1TSHRALDH1A1KMT2A | |
| SCHEMBL3943143 | 0.89 | RAB9A (0.51) | RAB9ANPC1CYP1A2CYP2D6TSHR | |
| SCHEMBL4029272 | 0.89 | RAB9A (0.50) | RAB9ANPC1CYP2D6ALDH1A1KMT2A | |
| SCHEMBL3942077 | 0.88 | RAB9A (0.55) | RAB9ANPC1ALDH1A1KMT2AACKR3 | |
| SCHEMBL3942150 | 0.87 | RAB9A (0.54) | RAB9ANPC1ALDH1A1KMT2AACKR3 | |
| SCHEMBL3949631 | 0.87 | HRH3 (0.50) | RAB9ANPC1CYP1A2CYP2D6TSHR | |
| SCHEMBL4359243 | 0.87 | ALDH1A1 (0.46) | NPC1TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL4036176 | 0.86 | ACKR3 (0.44) | RAB9ANPC1CYP1A2CYP2D6TSHR | |
| SCHEMBL3941064 | 0.86 | RAB9A (0.57) | RAB9ANPC1ALDH1A1KMT2AACKR3 | |
| SCHEMBL3944015 | 0.83 | RAB9A (0.58) | RAB9ANPC1ALDH1A1KMT2AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |