SCHEMBL4199991

SCHEMBL4199991

CC(=COc1ccc(Oc2ccccc2)cc1)C(=O)OCCCOc1ccc(-c2ccc(OCCCOC(=O)C(C)=COc3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.48
FFAR1 O14842 3/20 0.48
LTA4H P09960 4/20 0.46
PPARA Q07869 4/20 0.46
PPARD Q03181 3/20 0.45
PPARG P37231 2/20 0.44
HDAC3 O15379 4/20 0.43
HDAC4 P56524 4/20 0.43
HDAC1 Q13547 4/20 0.43
HDAC7 Q8WUI4 4/20 0.43
HDAC2 Q92769 4/20 0.43
HDAC10 Q969S8 4/20 0.43
HDAC11 Q96DB2 4/20 0.43
HDAC8 Q9BY41 4/20 0.43
HDAC6 Q9UBN7 4/20 0.43
HDAC9 Q9UKV0 4/20 0.43
HDAC5 Q9UQL6 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197206 0.96 HDAC1 (0.46) FFAR4FFAR1PPARAPPARDPPARG
SCHEMBL4197513 0.94 HDAC1 (0.49) LTA4HPPARAPPARDPPARGHDAC3
SCHEMBL4188598 0.94 HDAC1 (0.49) LTA4HPPARAPPARDPPARGHDAC3
SCHEMBL4198746 0.90 FFAR4 (0.53) FFAR4FFAR1LTA4HPPARAPPARD
SCHEMBL4184738 0.89 PPARD (0.46) FFAR4FFAR1PPARAPPARDPPARG
SCHEMBL4198143 0.88 FFAR4 (0.52) FFAR4FFAR1PPARAPPARDPPARG
SCHEMBL4188687 0.87 FFAR4 (0.50) FFAR4FFAR1PPARAPPARDPPARG
SCHEMBL4204186 0.86 PPARG (0.42) PPARAPPARDPPARGHDAC3HDAC4
SCHEMBL4194743 0.85 KDM4E (0.37) FFAR4FFAR1LTA4HPPARAPPARD
SCHEMBL4188678 0.85 FFAR4 (0.46) FFAR4PPARAPPARDPPARGHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 FFAR4 1889/4885FFAR1 1729/4885LTA4H 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.