SCHEMBL4200435

SCHEMBL4200435

CCC(N)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318974 0.73 ALDH1A1 (0.40) ALDH1A1ALOX15TSHRLMNA
SCHEMBL11142407 0.71 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRLMNA
SCHEMBL8601025 0.71 KMT2A (0.36) ALDH1A1LMNA
Isopropylamine SCHEMBL11360242 0.70 ALDH1A1 (0.57) ALDH1A1ALOX15TSHRLMNA
SCHEMBL6449607 0.69 ALDH1A1 (0.39) ALDH1A1ALOX15TSHRLMNA
SCHEMBL4259753 0.67 HRH3 (0.33)
SCHEMBL11311696 0.67 ALDH1A1 (0.38) ALDH1A1ALOX15TSHR
SCHEMBL5131454 0.66 ALDH1A1 (0.50) ALDH1A1ALOX15TSHR
SCHEMBL15133506 0.64 NR1I2 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL6551721 0.64 HRH4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130302873-A1 Methods of Making Material Coatings for Self-cleaning and Self-decontamination of Metal Surfaces U.S.A. AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE 2013-11-14 US disclosed
EP-2083955-A2 MATERIALS COATINGS AND METHODS FOR SELF-CLEANING AND SELF-DECONTAMINATION OF METAL SURFACES The Government of the United States of America as represented by the Secretary of the Navy (US) 2009-08-05 EP disclosed
US-20090010980-A1 Materials coatings and methods for self-cleaning and self-decontamination of metal surface NAVY, SECRETARY OF THE, THE U.S.A AS REPRESENTED BY THE 2009-01-08 US disclosed
WO-2008127289-A2 MATERIALS COATINGS AND METHODS FOR SELF-CLEANING AND SELF-DECONTAMINATION OF METAL SURFACES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-10-23 WO disclosed