Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586148 | 0.76 | NOS2 (0.41) | KMT2AKDM4ENOS3NOS2ALDH1A1 | |
| SCHEMBL31436573 | 0.73 | NOS2 (0.37) | KMT2AKDM4ENOS3NOS2ALDH1A1 | |
| SCHEMBL26598615 | 0.72 | ADORA2A (0.33) | KMT2ANOS3NOS2NOS1LMNA | |
| SCHEMBL30606159 | 0.72 | ADORA2A (0.33) | KMT2ANOS3NOS2NOS1LMNA | |
| SCHEMBL4200435 | 0.71 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL4259753 | 0.70 | HRH3 (0.33) | — | |
| SCHEMBL9378258 | 0.65 | NOS2 (0.44) | KMT2AKDM4ESMN1; SMN2NOS3NOS2 | |
| SCHEMBL115697 | 0.65 | — | — | |
| SCHEMBL22029272 | 0.64 | NOS2 (0.45) | KMT2AKDM4ESMN1; SMN2NOS3NOS2 | |
| SCHEMBL1221544 | 0.64 | NOS2 (0.46) | KMT2AKDM4ESMN1; SMN2NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5772990-A | Composition for slowing down the loss of hair based on pyrimidine N-oxides triaminosubstituted or their sulfoconjugated | L'OREAL (FR) | 1998-06-30 | — | — | US | disclosed |