SCHEMBL420046

SCHEMBL420046

O=P(O)(O)OP(=O)(O)OP(=O)(O)OC(Cl)CCCl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
BTN3A1 O00481 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780660 0.84
SCHEMBL3623749 0.80 SMPD1 (0.36)
SCHEMBL4956548 0.75 FDPS (0.36) FDPSBLMTDP1BTN3A1
SCHEMBL1651027 0.72 BTN3A1 (0.35) FDPSBLMTDP1BTN3A1
SCHEMBL30686 0.71 ALDH1A1 (0.36)
SCHEMBL897837 0.69 FDPS (0.64) FDPSBLMTDP1BTN3A1
SCHEMBL140392 0.69 FDPS (0.64) FDPSBLMTDP1BTN3A1
SCHEMBL8851949 0.69 FDPS (0.64) FDPSBLMTDP1BTN3A1
SCHEMBL45357 0.69 FDPS (0.64) FDPSBLMTDP1BTN3A1
SCHEMBL28767268 0.69 FDPS (0.64) FDPSBLMTDP1BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3469012-B9 AUTOCATALYTIC POLYOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-04-06 EP disclosed
EP-3469012-B1 AUTOCATALYTIC POLYOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-09-15 EP disclosed
US-10815331-B2 Autocatalytic polyols DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-27 US disclosed
EP-1817356-B2 ACID BLOCKED, AMINE BASED, AUTOCATALYTIC POLYOLS AND POLYURETHANE FOAMS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2020-08-19 EP disclosed
US-20190330405-A1 AUTOCATALYTIC POLYOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-31 US disclosed
EP-3469012-A1 AUTOCATALYTIC POLYOLS Dow Global Technologies, LLC (US) 2019-04-17 EP disclosed
EP-3126428-B1 POLYETHER POLYOL PROVIDING GOOD BLOW-GEL BALANCE FOR POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-06 EP disclosed
US-20180148535-A1 AUTOCATALYTIC POLYOL USEFUL FOR POLYURETHANE FOAM MANUFACTURE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-31 US disclosed
EP-3310830-A1 AUTOCATALYTIC POLYOL USEFUL FOR POLYURETHANE FOAM MANUFACTURE Dow Global Technologies LLC (US) 2018-04-25 EP disclosed
WO-2017218254-A1 AUTOCATALYTIC POLYOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-21 WO disclosed
US-20040242832-A1 Autocatalytic polyols with gelling characteristics and polyurethane products made therefrom CASATI FRANCOIS M (CH) 2004-12-02 US disclosed
EP-1282658-B1 INTEGRAL SKIN FOAMS EMPLOYING PENTAFLUOROBUTANE BLOWING AGENTS DOW GLOBAL TECHNOLOGIES INC (US) 2004-11-17 EP disclosed
US-6762274-B2 Auto-catalytic polyols based on tertiary amine initiators are reacted with polyisocyanates in the presence of other additives and/or auxiliary agents known per se to produce polyurethane products DOW GLOBAL TECHNOLOGIES INC. 2004-07-13 US disclosed
US-6759444-B2 POLYURETHANE MOLDINGS; ABRASION AND CRACKING RESISTANCE DOW GLOBAL TECHNOLOGIES INC. 2004-07-06 US disclosed
US-20040102535-A1 Polyols with autocatalytic characteristics and polyurethane products made therefrom DOW GLOBAL TECHNOLOGIES LLC 2004-05-27 US disclosed
WO-2004026948-A2 FIRE RESISTANT POLYMERIC FOAM COMPOSITES DOW GLOBAL TECHNOLOGIES INC. (US) 2004-04-01 WO disclosed
US-20030100699-A1 Low emission polyurethane polymers made with autocatalytic polyols DOW GLOBAL TECHNOLOGIES LLC 2003-05-29 US disclosed
US-20030055118-A1 Integral skin foams employing pentafluorobutane blowing agents DOW GLOBAL TECHNOLOGIES LLC 2003-03-20 US disclosed
EP-1268598-A1 LOW EMISSION POLYURETHANE POLYMERS MADE WITH AUTOCATALYTIC POLYOLS THE DOW CHEMICAL COMPANY (US) 2003-01-02 EP disclosed
WO-2001058976-A1 LOW EMISSION POLYURETHANE POLYMERS MADE WITH AUTOCATALYTIC POLYOLS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-08-16 WO disclosed